Quality-control pathway unlocked

Cryptology Unlocked Cryptology Unlocked

Algorithms Unlocked

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Uterine closure with unlocked suture in cesarean section: Safety and Quality

OBJECTIVE Comparing locked and unlocked uterine closure techniques in terms of bleeding control and uterine incision healing. METHODS The patients undergoing cesarean section in Sifa University Hospital between May - October 2012 were accepted to this prospective controlled study. Primarily, safety was evaluated. The hemoglobin count (HC) and serum creatine kinase (CK) levels of the patients ...

Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life

Aging entails a progressive decline in protein homeostasis, which often leads to age-related diseases. The endoplasmic reticulum (ER) is the site of protein synthesis and maturation for secreted and membrane proteins. Correct folding of ER proteins requires covalent attachment of N-linked glycan oligosaccharides. Here, we report that increased synthesis of N-glycan precursors in the hexosamine ...

A new pathway for mitochondrial quality control: mitochondrial-derived vesicles.

The last decade has been marked by tremendous progress in our understanding of the cell biology of mitochondria, with the identification of molecules and mechanisms that regulate their fusion, fission, motility, and the architectural transitions within the inner membrane. More importantly, the manipulation of these machineries in tissues has provided links between mitochondrial dynamics and phy...